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  Autism Society of the Philippines

Research list
Aripiprazole in Pervasive Developmental Disorder Not Otherwise Specified and Asperger’s Disorder: A 14-Week, Prospective, Open-Label Study

Authored by Stigler, KA, Diener JT, Kohn AE, Li L., Erickson CA, Posey DJ, and McDougle CJ in Journal of Child and Adolescent Psychopharmacology, Volume 19, Issue 3, p. 265-274, (2009).

Article summary (posted Jul 22, 2010):


Aripiprazole may help to improve severe irritability in children with pervasive developmental disorder not otherwise specified (PDD-NOS) and Asperger syndrome.

This prospective, open-label study sought to find out if the drug aripiprazole was safe and helpful as a treatment for irritability in children with PDD-NOS and Asperger syndrome. The 14-week study found that aripiprazole was safe and may be helpful for such patients. The patients showed decreased irritability as well as increased social behavior. The authors note that there are not many studies of patients with PDD-NOS (as opposed to autism). PDD-NOS is the most common subtype of PDD and the authors called for more studies of these patients.


You can access the original abstract and the complete paper is sometimes available for free via Google Scholar (look for entries that say "PDF").


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